GC-MS quantitation designed for reproducible research workflows
GC-AutoFit is a GC-MS quantitation service for biological samples, currently available for urine, with serum introduced as a new release and additional biospecimen matrices planned for future rollout.
The platform is designed for researchers who need a reproducible, transparent workflow for targeted analysis across heterogeneous biological matrices, while keeping the public release aligned with what is currently validated and available.
Additional matrices will be introduced only after validation and release review.
Validated compounds only, with additional analytes added after review and verification.
Presented as a validated research workflow rather than a clinical diagnostic assay.
Built for method clarity, reproducibility, and downstream interpretation.
What the service does
The platform streamlines the path from raw GC-MS spectra to metabolite-level quantitative results. It is intended for researchers who need a controlled and repeatable analytical workflow, while keeping each released matrix tied to current validation status rather than broad availability claims. The current release supports quantitative detection of up to 150 metabolites in total. This panel is intentionally scoped to compounds that have been validated for the present service release, and it will expand as additional analytes complete review and verification. At present, urine is the primary supported biofluid, serum has been introduced as a new release, and additional matrices such as fecal extracts and CSF are planned for later release after validation.
Scientific scope
GC-AutoFit is being introduced alongside a research publication that establishes the analytical and computational groundwork for the service. The framing is intentionally conservative so the workflow can be evaluated clearly by the metabolomics community before broader expansion.
- Emphasis on targeted quantitation rather than untargeted claims.
- Explicit reporting of current coverage, limits, and supported sample types.
- Designed to support peer review, reproducibility, and downstream biological interpretation.
Service profile
- Supports targeted GC-MS quantitation with staged matrix-specific releases.
- Prioritizes reproducible processing and reviewable output over broad marketing claims.
- Structured for analytical labs and researchers who need consistent batch handling.
Next steps
Additional metabolites and workflow refinements will be added in future releases after validation. The long-term goal is to provide a scalable, publication-ready GC-MS quantitation service that keeps pace with expanding metabolomics studies while preserving method rigor.
Operating principles
The service is being developed with a practical analytical mindset: clearly defined scope, explicit assumptions, and output that can be inspected by both domain scientists and reviewers.
That means the page language is intentionally careful. It describes what is currently supported, what has been validated, and how the platform should be interpreted in a research context.